null

SMILES: COc1cc2c(N3CCN(CC3)C(=S)Nc3ccc(cc3)C#N)c(cnc2cc1OCCCN1CCCCC1)C#N

InChI Key: InChIKey=ZJOHAEZPXFNGLV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152361   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50152361 (4-[3-Cyano-6-methoxy-7-(3-piperidin-1-yl-propoxy)-...) Show SMILES COc1cc2c(N3CCN(CC3)C(=S)Nc3ccc(cc3)C#N)c(cnc2cc1OCCCN1CCCCC1)C#N Show InChI InChI=1S/C31H35N7O2S/c1-39-28-18-26-27(19-29(28)40-17-5-12-36-10-3-2-4-11-36)34-22-24(21-33)30(26)37-13-15-38(16-14-37)31(41)35-25-8-6-23(20-32)7-9-25/h6-9,18-19,22H,2-5,10-17H2,1H3,(H,35,41)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
and In Vivo Sciences Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Platelet derived growth factor receptor beta autophosphorylation in MG-63 cells with 45% human plasma				Bioorg Med Chem Lett 14: 4867-72 (2004) Article DOI: 10.1016/j.bmcl.2004.07.041 BindingDB Entry DOI: 10.7270/Q2VM4BQN
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50152361 (4-[3-Cyano-6-methoxy-7-(3-piperidin-1-yl-propoxy)-...) Show SMILES COc1cc2c(N3CCN(CC3)C(=S)Nc3ccc(cc3)C#N)c(cnc2cc1OCCCN1CCCCC1)C#N Show InChI InChI=1S/C31H35N7O2S/c1-39-28-18-26-27(19-29(28)40-17-5-12-36-10-3-2-4-11-36)34-22-24(21-33)30(26)37-13-15-38(16-14-37)31(41)35-25-8-6-23(20-32)7-9-25/h6-9,18-19,22H,2-5,10-17H2,1H3,(H,35,41)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
and In Vivo Sciences Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Platelet derived growth factor receptor beta autophosphorylation in MG-63 cells without plasma				Bioorg Med Chem Lett 14: 4867-72 (2004) Article DOI: 10.1016/j.bmcl.2004.07.041 BindingDB Entry DOI: 10.7270/Q2VM4BQN
					More data for this Ligand-Target Pair