null

SMILES: COc1cc2c(N3CCN(CC3)C(=S)Nc3ccc(cc3)-c3ccccn3)c(cnc2cc1OCCCN1CCCCC1)C#N

InChI Key: InChIKey=AQTCOACEVKFRNO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152366   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50152366 (4-[3-Cyano-6-methoxy-7-(3-piperidin-1-yl-propoxy)-...) Show SMILES COc1cc2c(N3CCN(CC3)C(=S)Nc3ccc(cc3)-c3ccccn3)c(cnc2cc1OCCCN1CCCCC1)C#N Show InChI InChI=1S/C35H39N7O2S/c1-43-32-22-29-31(23-33(32)44-21-7-16-40-14-5-2-6-15-40)38-25-27(24-36)34(29)41-17-19-42(20-18-41)35(45)39-28-11-9-26(10-12-28)30-8-3-4-13-37-30/h3-4,8-13,22-23,25H,2,5-7,14-21H2,1H3,(H,39,45)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
and In Vivo Sciences Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Platelet derived growth factor receptor beta autophosphorylation in MG-63 cells with 45% human plasma				Bioorg Med Chem Lett 14: 4867-72 (2004) Article DOI: 10.1016/j.bmcl.2004.07.041 BindingDB Entry DOI: 10.7270/Q2VM4BQN
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50152366 (4-[3-Cyano-6-methoxy-7-(3-piperidin-1-yl-propoxy)-...) Show SMILES COc1cc2c(N3CCN(CC3)C(=S)Nc3ccc(cc3)-c3ccccn3)c(cnc2cc1OCCCN1CCCCC1)C#N Show InChI InChI=1S/C35H39N7O2S/c1-43-32-22-29-31(23-33(32)44-21-7-16-40-14-5-2-6-15-40)38-25-27(24-36)34(29)41-17-19-42(20-18-41)35(45)39-28-11-9-26(10-12-28)30-8-3-4-13-37-30/h3-4,8-13,22-23,25H,2,5-7,14-21H2,1H3,(H,39,45)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
and In Vivo Sciences Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Platelet derived growth factor receptor beta autophosphorylation in MG-63 cells without plasma				Bioorg Med Chem Lett 14: 4867-72 (2004) Article DOI: 10.1016/j.bmcl.2004.07.041 BindingDB Entry DOI: 10.7270/Q2VM4BQN
					More data for this Ligand-Target Pair