null

SMILES: COc1cc2c(ncnc2cc1OCCCN1CCCCC1)N1CCN(CC1)C(=S)NCc1csc(n1)-c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=ASOIAJVDWJWXOF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152372   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50152372 (4-[6-Methoxy-7-(3-piperidin-1-yl-propoxy)-quinazol...) Show SMILES COc1cc2c(ncnc2cc1OCCCN1CCCCC1)N1CCN(CC1)C(=S)NCc1csc(n1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C33H38F3N7O2S2/c1-44-28-18-26-27(19-29(28)45-17-5-12-41-10-3-2-4-11-41)38-22-39-30(26)42-13-15-43(16-14-42)32(46)37-20-25-21-47-31(40-25)23-6-8-24(9-7-23)33(34,35)36/h6-9,18-19,21-22H,2-5,10-17,20H2,1H3,(H,37,46)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
and In Vivo Sciences Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Platelet derived growth factor receptor beta autophosphorylation in MG-63 cells with 45% human plasma				Bioorg Med Chem Lett 14: 4867-72 (2004) Article DOI: 10.1016/j.bmcl.2004.07.041 BindingDB Entry DOI: 10.7270/Q2VM4BQN
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50152372 (4-[6-Methoxy-7-(3-piperidin-1-yl-propoxy)-quinazol...) Show SMILES COc1cc2c(ncnc2cc1OCCCN1CCCCC1)N1CCN(CC1)C(=S)NCc1csc(n1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C33H38F3N7O2S2/c1-44-28-18-26-27(19-29(28)45-17-5-12-41-10-3-2-4-11-41)38-22-39-30(26)42-13-15-43(16-14-42)32(46)37-20-25-21-47-31(40-25)23-6-8-24(9-7-23)33(34,35)36/h6-9,18-19,21-22H,2-5,10-17,20H2,1H3,(H,37,46)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
and In Vivo Sciences Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Platelet derived growth factor receptor beta autophosphorylation in MG-63 cells without plasma				Bioorg Med Chem Lett 14: 4867-72 (2004) Article DOI: 10.1016/j.bmcl.2004.07.041 BindingDB Entry DOI: 10.7270/Q2VM4BQN
					More data for this Ligand-Target Pair