null

SMILES: COc1cc2c(ncnc2cc1OCCN1CCCCC1)N1CCN(CC1)C(=[SH+])[N-]c1ccc(cc1)-c1cccc[n+]1[O-]

InChI Key: InChIKey=SDBGVSFHOMJSOL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152375   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50152375 (4-[6-Methoxy-7-(2-piperidin-1-yl-ethoxy)-quinazoli...) Show SMILES COc1cc2c(ncnc2cc1OCCN1CCCCC1)N1CCN(CC1)C(=[SH+])[N-]c1ccc(cc1)-c1cccc[n+]1[O-] Show InChI InChI=1S/C32H37N7O3S/c1-41-29-21-26-27(22-30(29)42-20-19-36-12-4-2-5-13-36)33-23-34-31(26)37-15-17-38(18-16-37)32(43)35-25-10-8-24(9-11-25)28-7-3-6-14-39(28)40/h3,6-11,14,21-23H,2,4-5,12-13,15-20H2,1H3,(H,35,43)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
and In Vivo Sciences Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Platelet derived growth factor receptor beta autophosphorylation in MG-63 cells without plasma				Bioorg Med Chem Lett 14: 4867-72 (2004) Article DOI: 10.1016/j.bmcl.2004.07.041 BindingDB Entry DOI: 10.7270/Q2VM4BQN
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50152375 (4-[6-Methoxy-7-(2-piperidin-1-yl-ethoxy)-quinazoli...) Show SMILES COc1cc2c(ncnc2cc1OCCN1CCCCC1)N1CCN(CC1)C(=[SH+])[N-]c1ccc(cc1)-c1cccc[n+]1[O-] Show InChI InChI=1S/C32H37N7O3S/c1-41-29-21-26-27(22-30(29)42-20-19-36-12-4-2-5-13-36)33-23-34-31(26)37-15-17-38(18-16-37)32(43)35-25-10-8-24(9-11-25)28-7-3-6-14-39(28)40/h3,6-11,14,21-23H,2,4-5,12-13,15-20H2,1H3,(H,35,43)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
and In Vivo Sciences Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Platelet derived growth factor receptor beta autophosphorylation in MG-63 cells with 45% human plasma				Bioorg Med Chem Lett 14: 4867-72 (2004) Article DOI: 10.1016/j.bmcl.2004.07.041 BindingDB Entry DOI: 10.7270/Q2VM4BQN
					More data for this Ligand-Target Pair