BDBM50152393 4-[6-Methoxy-7-(2-piperidin-1-yl-ethoxy)-quinazolin-4-yl]-piperazine-1-carbothioic acid 4-pyridin-3-yl-benzylamide::CHEMBL184382

SMILES: COc1cc2c(ncnc2cc1OCCN1CCCCC1)N1CCN(CC1)C(=S)NCc1ccc(cc1)-c1cccnc1

InChI Key: InChIKey=UCNSWYNASPIUFL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152393   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50152393 (4-[6-Methoxy-7-(2-piperidin-1-yl-ethoxy)-quinazoli...) Show SMILES COc1cc2c(ncnc2cc1OCCN1CCCCC1)N1CCN(CC1)C(=S)NCc1ccc(cc1)-c1cccnc1 Show InChI InChI=1S/C33H39N7O2S/c1-41-30-20-28-29(21-31(30)42-19-18-38-12-3-2-4-13-38)36-24-37-32(28)39-14-16-40(17-15-39)33(43)35-22-25-7-9-26(10-8-25)27-6-5-11-34-23-27/h5-11,20-21,23-24H,2-4,12-19,22H2,1H3,(H,35,43)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.48E+4	n/a	n/a	n/a	n/a	n/a	n/a
and In Vivo Sciences Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Platelet derived growth factor receptor beta autophosphorylation in MG-63 cells without plasma				Bioorg Med Chem Lett 14: 4867-72 (2004) Article DOI: 10.1016/j.bmcl.2004.07.041 BindingDB Entry DOI: 10.7270/Q2VM4BQN
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50152393 (4-[6-Methoxy-7-(2-piperidin-1-yl-ethoxy)-quinazoli...) Show SMILES COc1cc2c(ncnc2cc1OCCN1CCCCC1)N1CCN(CC1)C(=S)NCc1ccc(cc1)-c1cccnc1 Show InChI InChI=1S/C33H39N7O2S/c1-41-30-20-28-29(21-31(30)42-19-18-38-12-3-2-4-13-38)36-24-37-32(28)39-14-16-40(17-15-39)33(43)35-22-25-7-9-26(10-8-25)27-6-5-11-34-23-27/h5-11,20-21,23-24H,2-4,12-19,22H2,1H3,(H,35,43)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
and In Vivo Sciences Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Platelet derived growth factor receptor beta autophosphorylation in MG-63 cells with 45% human plasma				Bioorg Med Chem Lett 14: 4867-72 (2004) Article DOI: 10.1016/j.bmcl.2004.07.041 BindingDB Entry DOI: 10.7270/Q2VM4BQN
					More data for this Ligand-Target Pair