null

SMILES: COc1cc2c(N3CCN(CC3)C(=S)Nc3ccncc3)c(cnc2cc1OCCCN1CCCCC1)C#N

InChI Key: InChIKey=UFHXBIRJFNKOQK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152396   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50152396 (4-[3-Cyano-6-methoxy-7-(3-piperidin-1-yl-propoxy)-...) Show SMILES COc1cc2c(N3CCN(CC3)C(=S)Nc3ccncc3)c(cnc2cc1OCCCN1CCCCC1)C#N Show InChI InChI=1S/C29H35N7O2S/c1-37-26-18-24-25(19-27(26)38-17-5-12-34-10-3-2-4-11-34)32-21-22(20-30)28(24)35-13-15-36(16-14-35)29(39)33-23-6-8-31-9-7-23/h6-9,18-19,21H,2-5,10-17H2,1H3,(H,31,33,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
and In Vivo Sciences Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Platelet derived growth factor receptor beta autophosphorylation in MG-63 cells without plasma				Bioorg Med Chem Lett 14: 4867-72 (2004) Article DOI: 10.1016/j.bmcl.2004.07.041 BindingDB Entry DOI: 10.7270/Q2VM4BQN
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50152396 (4-[3-Cyano-6-methoxy-7-(3-piperidin-1-yl-propoxy)-...) Show SMILES COc1cc2c(N3CCN(CC3)C(=S)Nc3ccncc3)c(cnc2cc1OCCCN1CCCCC1)C#N Show InChI InChI=1S/C29H35N7O2S/c1-37-26-18-24-25(19-27(26)38-17-5-12-34-10-3-2-4-11-34)32-21-22(20-30)28(24)35-13-15-36(16-14-35)29(39)33-23-6-8-31-9-7-23/h6-9,18-19,21H,2-5,10-17H2,1H3,(H,31,33,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
and In Vivo Sciences Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Platelet derived growth factor receptor beta autophosphorylation in MG-63 cells with 45% human plasma				Bioorg Med Chem Lett 14: 4867-72 (2004) Article DOI: 10.1016/j.bmcl.2004.07.041 BindingDB Entry DOI: 10.7270/Q2VM4BQN
					More data for this Ligand-Target Pair