BindingDB logo
myBDB logout

BDBM50152481 8-[2-(3-Methoxy-benzylamino)-1-methyl-ethoxy]-quinolin-2-ylamine::CHEMBL183032

SMILES: COc1cccc(CNCC(C)Oc2cccc3ccc(N)nc23)c1

InChI Key: InChIKey=JHYPBALOYBGABT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50152481   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor


(Homo sapiens (Human))		BDBM50152481
PNG
(8-[2-(3-Methoxy-benzylamino)-1-methyl-ethoxy]-quin...)
Show SMILES COc1cccc(CNCC(C)Oc2cccc3ccc(N)nc23)c1
Show InChI InChI=1S/C20H23N3O2/c1-14(12-22-13-15-5-3-7-17(11-15)24-2)25-18-8-4-6-16-9-10-19(21)23-20(16)18/h3-11,14,22H,12-13H2,1-2H3,(H2,21,23)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human Melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4879-82 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.034
BindingDB Entry DOI: 10.7270/Q2M32V61
More data for this
Ligand-Target Pair