BDBM50152512 CHEMBL185251::{1-[4-(7-Fluoro-4-methyl-3,4-dihydro-2H-benzo[1,4]oxazin-2-ylmethoxy)-benzoyl]-2-methyl-1H-indol-4-yl}-acetic acid
SMILES: CN1C[C@@H](COc2ccc(cc2)C(=O)n2c(C)cc3c(CC(O)=O)cccc23)Oc2cc(F)ccc12
InChI Key: InChIKey=OOSKJUCSXNQQLG-QFIPXVFZSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Prostanoid DP receptor (Homo sapiens (Human)) | BDBM50152512 (CHEMBL185251 | {1-[4-(7-Fluoro-4-methyl-3,4-dihydr...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing human Prostaglandin D2 receptor | Bioorg Med Chem Lett 14: 4891-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.039 BindingDB Entry DOI: 10.7270/Q2BK1BTV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid DP receptor (Mus musculus) | BDBM50152512 (CHEMBL185251 | {1-[4-(7-Fluoro-4-methyl-3,4-dihydr...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin D2 receptor | Bioorg Med Chem Lett 14: 4891-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.039 BindingDB Entry DOI: 10.7270/Q2BK1BTV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP3 Receptor (Mus musculus (Mouse)) | BDBM50152512 (CHEMBL185251 | {1-[4-(7-Fluoro-4-methyl-3,4-dihydr...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP3 | Bioorg Med Chem Lett 14: 4891-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.039 BindingDB Entry DOI: 10.7270/Q2BK1BTV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP2 Receptor (Mus musculus (Mouse)) | BDBM50152512 (CHEMBL185251 | {1-[4-(7-Fluoro-4-methyl-3,4-dihydr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP2 | Bioorg Med Chem Lett 14: 4891-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.039 BindingDB Entry DOI: 10.7270/Q2BK1BTV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP1 Receptor (Mus musculus (Mouse)) | BDBM50152512 (CHEMBL185251 | {1-[4-(7-Fluoro-4-methyl-3,4-dihydr...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP1 | Bioorg Med Chem Lett 14: 4891-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.039 BindingDB Entry DOI: 10.7270/Q2BK1BTV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP4 Receptor (Mus musculus (Mouse)) | BDBM50152512 (CHEMBL185251 | {1-[4-(7-Fluoro-4-methyl-3,4-dihydr...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP4 | Bioorg Med Chem Lett 14: 4891-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.039 BindingDB Entry DOI: 10.7270/Q2BK1BTV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid DP receptor (Homo sapiens (Human)) | BDBM50152512 (CHEMBL185251 | {1-[4-(7-Fluoro-4-methyl-3,4-dihydr...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.810 | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Effect on the increase in cAMP formation induced by PGD-2 in the presence of bovine serum albumin in CHO cells expressing human Prostaglandin D2 rece... | Bioorg Med Chem Lett 14: 4891-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.039 BindingDB Entry DOI: 10.7270/Q2BK1BTV | |||||||||||
More data for this Ligand-Target Pair |