BDBM50152552 4-(2,3-Dichloro-phenyl)-2,4-dioxo-butyric acid::CHEMBL185879
SMILES: OC(=O)C(=O)CC(=O)c1cccc(Cl)c1Cl
InChI Key: InChIKey=ULJWKEWRQXXYJV-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA excision repair protein ERCC-5 (Homo sapiens (Human)) | BDBM50152552 (4-(2,3-Dichloro-phenyl)-2,4-dioxo-butyric acid | C...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.21E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc. Curated by ChEMBL | Assay Description Concentration required for 50% inhibition of Xeroderma pigmentosum G | Bioorg Med Chem Lett 14: 4915-8 (2004) Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Flap endonuclease 1 (Homo sapiens (Human)) | BDBM50152552 (4-(2,3-Dichloro-phenyl)-2,4-dioxo-butyric acid | C...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.77E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc. Curated by ChEMBL | Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 | Bioorg Med Chem Lett 14: 4915-8 (2004) Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF | |||||||||||
More data for this Ligand-Target Pair |