BDBM50152557 2,4-Dioxo-4-[5-(4-trifluoromethoxy-phenyl)-thiophen-2-yl]-butyric acid::CHEMBL182756

SMILES: OC(=O)C(=O)CC(=O)c1ccc(s1)-c1ccc(OC(F)(F)F)cc1

InChI Key: InChIKey=CBRIPJMCSCGSGW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152557   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Flap endonuclease 1 (Homo sapiens (Human))	BDBM50152557 (2,4-Dioxo-4-[5-(4-trifluoromethoxy-phenyl)-thiophe...) Show SMILES OC(=O)C(=O)CC(=O)c1ccc(s1)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C15H9F3O5S/c16-15(17,18)23-9-3-1-8(2-4-9)12-5-6-13(24-12)10(19)7-11(20)14(21)22/h1-6H,7H2,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of Flap endonuclease-1				Bioorg Med Chem Lett 14: 4915-8 (2004) Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF
					More data for this Ligand-Target Pair
DNA excision repair protein ERCC-5 (Homo sapiens (Human))	BDBM50152557 (2,4-Dioxo-4-[5-(4-trifluoromethoxy-phenyl)-thiophe...) Show SMILES OC(=O)C(=O)CC(=O)c1ccc(s1)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C15H9F3O5S/c16-15(17,18)23-9-3-1-8(2-4-9)12-5-6-13(24-12)10(19)7-11(20)14(21)22/h1-6H,7H2,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of Xeroderma pigmentosum G				Bioorg Med Chem Lett 14: 4915-8 (2004) Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF
					More data for this Ligand-Target Pair