BDBM50152566 4-[5-(4-tert-Butyl-phenyl)-furan-2-yl]-2,4-dioxo-butyric acid::CHEMBL185566

SMILES: CC(C)(C)c1ccc(cc1)-c1ccc(o1)C(=O)CC(=O)C(O)=O

InChI Key: InChIKey=XLGFKEGWQLHSTR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152566   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA excision repair protein ERCC-5 (Homo sapiens (Human))	BDBM50152566 (4-[5-(4-tert-Butyl-phenyl)-furan-2-yl]-2,4-dioxo-b...) Show SMILES CC(C)(C)c1ccc(cc1)-c1ccc(o1)C(=O)CC(=O)C(O)=O Show InChI InChI=1S/C18H18O5/c1-18(2,3)12-6-4-11(5-7-12)15-8-9-16(23-15)13(19)10-14(20)17(21)22/h4-9H,10H2,1-3H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of Xeroderma pigmentosum G				Bioorg Med Chem Lett 14: 4915-8 (2004) Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF
					More data for this Ligand-Target Pair
Flap endonuclease 1 (Homo sapiens (Human))	BDBM50152566 (4-[5-(4-tert-Butyl-phenyl)-furan-2-yl]-2,4-dioxo-b...) Show SMILES CC(C)(C)c1ccc(cc1)-c1ccc(o1)C(=O)CC(=O)C(O)=O Show InChI InChI=1S/C18H18O5/c1-18(2,3)12-6-4-11(5-7-12)15-8-9-16(23-15)13(19)10-14(20)17(21)22/h4-9H,10H2,1-3H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of Flap endonuclease-1				Bioorg Med Chem Lett 14: 4915-8 (2004) Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF
					More data for this Ligand-Target Pair