BDBM50152880 2-(4-Methoxy-benzylsulfanyl)-6-trifluoromethyl-pyrimidin-4-ol::CHEMBL184136
SMILES: COc1ccc(CSc2nc(cc(=O)[nH]2)C(F)(F)F)cc1
InChI Key: InChIKey=CNCRMWAVZITOLY-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fatty acid binding protein muscle (Homo sapiens (Human)) | BDBM50152880 (2-(4-Methoxy-benzylsulfanyl)-6-trifluoromethyl-pyr...) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB Curated by ChEMBL | Assay Description In vitro inhibitory concentration against H-FABP (human-heart and muscle fatty acid binding protein) | Bioorg Med Chem Lett 14: 4449-52 (2004) Article DOI: 10.1016/j.bmcl.2004.06.058 BindingDB Entry DOI: 10.7270/Q2SN08FF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty acid-binding protein 4 (FABP4) (Homo sapiens (Human)) | BDBM50152880 (2-(4-Methoxy-benzylsulfanyl)-6-trifluoromethyl-pyr...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB Curated by ChEMBL | Assay Description In vitro inhibitory concentration against A-FABP (Adipocyte fatty acid binding protein) | Bioorg Med Chem Lett 14: 4449-52 (2004) Article DOI: 10.1016/j.bmcl.2004.06.058 BindingDB Entry DOI: 10.7270/Q2SN08FF | |||||||||||
More data for this Ligand-Target Pair |