BDBM50153116 CHEMBL3774672

SMILES: OCCc1cnn(c1)-c1nccc2c1nc[nH]c2=O

InChI Key: InChIKey=GSQZSUZKJWHBOL-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50153116   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM50153116 (CHEMBL3774672) Show SMILES OCCc1cnn(c1)-c1nccc2c1nc[nH]c2=O Show InChI InChI=1S/C12H11N5O2/c18-4-2-8-5-16-17(6-8)11-10-9(1-3-13-11)12(19)15-7-14-10/h1,3,5-7,18H,2,4H2,(H,14,15,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 1388-409 (2016) BindingDB Entry DOI: 10.7270/Q2W097TR
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5C (Homo sapiens (Human))	BDBM50153116 (CHEMBL3774672) Show SMILES OCCc1cnn(c1)-c1nccc2c1nc[nH]c2=O Show InChI InChI=1S/C12H11N5O2/c18-4-2-8-5-16-17(6-8)11-10-9(1-3-13-11)12(19)15-7-14-10/h1,3,5-7,18H,2,4H2,(H,14,15,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 1388-409 (2016) BindingDB Entry DOI: 10.7270/Q2W097TR
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4A (Homo sapiens (Human))	BDBM50153116 (CHEMBL3774672) Show SMILES OCCc1cnn(c1)-c1nccc2c1nc[nH]c2=O Show InChI InChI=1S/C12H11N5O2/c18-4-2-8-5-16-17(6-8)11-10-9(1-3-13-11)12(19)15-7-14-10/h1,3,5-7,18H,2,4H2,(H,14,15,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human N-terminal His-tagged KDM4A (1 to 359 residues) expressed in Escherichia coli using biotin-H3K9me3 as substrate preincubated for ...				J Med Chem 59: 1388-409 (2016) BindingDB Entry DOI: 10.7270/Q2W097TR
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4B (Homo sapiens (Human))	BDBM50153116 (CHEMBL3774672) Show SMILES OCCc1cnn(c1)-c1nccc2c1nc[nH]c2=O Show InChI InChI=1S/C12H11N5O2/c18-4-2-8-5-16-17(6-8)11-10-9(1-3-13-11)12(19)15-7-14-10/h1,3,5-7,18H,2,4H2,(H,14,15,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...				J Med Chem 59: 1388-409 (2016) BindingDB Entry DOI: 10.7270/Q2W097TR
					More data for this Ligand-Target Pair