Found 6 hits for monomerid = 50153131 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50153131
(CHEMBL185415 | {1-[1-(4-Isopropyl-cyclohexyl)-pipe...)Show SMILES CC(C)C1CCC(CC1)N1CCC(CC1)N1c2ccccc2CN(CC#N)S1(=O)=O |(1.34,-9.03,;-.02,-8.25,;-1.35,-9.05,;-.04,-6.71,;-1.37,-5.95,;-1.37,-4.4,;-.04,-3.62,;1.29,-4.4,;1.29,-5.95,;-.04,-2.07,;-1.39,-1.36,;-1.43,.21,;-.11,1.01,;1.25,.27,;1.27,-1.29,;-.14,2.55,;-1.49,3.27,;-2.8,2.46,;-4.13,3.2,;-4.18,4.75,;-2.87,5.54,;-1.51,4.79,;-.23,5.6,;1.13,4.86,;2.44,5.67,;3.8,4.95,;5.14,4.19,;1.17,3.34,;2.65,3.74,;1.57,1.85,)| Show InChI InChI=1S/C23H34N4O2S/c1-18(2)19-7-9-21(10-8-19)25-14-11-22(12-15-25)27-23-6-4-3-5-20(23)17-26(16-13-24)30(27,28)29/h3-6,18-19,21-22H,7-12,14-17H2,1-2H3 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue Pharma LP
Curated by ChEMBL
| Assay Description Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1 |
Bioorg Med Chem Lett 14: 5045-50 (2004)
Article DOI: 10.1016/j.bmcl.2004.08.001 BindingDB Entry DOI: 10.7270/Q2TM7BV8 |
More data for this Ligand-Target Pair | |
Nociceptin receptor
(Homo sapiens (Human)) | BDBM50153131
(CHEMBL185415 | {1-[1-(4-Isopropyl-cyclohexyl)-pipe...)Show SMILES CC(C)C1CCC(CC1)N1CCC(CC1)N1c2ccccc2CN(CC#N)S1(=O)=O |(1.34,-9.03,;-.02,-8.25,;-1.35,-9.05,;-.04,-6.71,;-1.37,-5.95,;-1.37,-4.4,;-.04,-3.62,;1.29,-4.4,;1.29,-5.95,;-.04,-2.07,;-1.39,-1.36,;-1.43,.21,;-.11,1.01,;1.25,.27,;1.27,-1.29,;-.14,2.55,;-1.49,3.27,;-2.8,2.46,;-4.13,3.2,;-4.18,4.75,;-2.87,5.54,;-1.51,4.79,;-.23,5.6,;1.13,4.86,;2.44,5.67,;3.8,4.95,;5.14,4.19,;1.17,3.34,;2.65,3.74,;1.57,1.85,)| Show InChI InChI=1S/C23H34N4O2S/c1-18(2)19-7-9-21(10-8-19)25-14-11-22(12-15-25)27-23-6-4-3-5-20(23)17-26(16-13-24)30(27,28)29/h3-6,18-19,21-22H,7-12,14-17H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue Pharma LP
Curated by ChEMBL
| Assay Description Inhibition of [3H]nociceptin binding to human Opioid receptor like 1 |
Bioorg Med Chem Lett 14: 5045-50 (2004)
Article DOI: 10.1016/j.bmcl.2004.08.001 BindingDB Entry DOI: 10.7270/Q2TM7BV8 |
More data for this Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50153131
(CHEMBL185415 | {1-[1-(4-Isopropyl-cyclohexyl)-pipe...)Show SMILES CC(C)C1CCC(CC1)N1CCC(CC1)N1c2ccccc2CN(CC#N)S1(=O)=O |(1.34,-9.03,;-.02,-8.25,;-1.35,-9.05,;-.04,-6.71,;-1.37,-5.95,;-1.37,-4.4,;-.04,-3.62,;1.29,-4.4,;1.29,-5.95,;-.04,-2.07,;-1.39,-1.36,;-1.43,.21,;-.11,1.01,;1.25,.27,;1.27,-1.29,;-.14,2.55,;-1.49,3.27,;-2.8,2.46,;-4.13,3.2,;-4.18,4.75,;-2.87,5.54,;-1.51,4.79,;-.23,5.6,;1.13,4.86,;2.44,5.67,;3.8,4.95,;5.14,4.19,;1.17,3.34,;2.65,3.74,;1.57,1.85,)| Show InChI InChI=1S/C23H34N4O2S/c1-18(2)19-7-9-21(10-8-19)25-14-11-22(12-15-25)27-23-6-4-3-5-20(23)17-26(16-13-24)30(27,28)29/h3-6,18-19,21-22H,7-12,14-17H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue Pharma LP
Curated by ChEMBL
| Assay Description Inhibition of [3H]U-69593 binding to human Opioid receptor kappa 1 |
Bioorg Med Chem Lett 14: 5045-50 (2004)
Article DOI: 10.1016/j.bmcl.2004.08.001 BindingDB Entry DOI: 10.7270/Q2TM7BV8 |
More data for this Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50153131
(CHEMBL185415 | {1-[1-(4-Isopropyl-cyclohexyl)-pipe...)Show SMILES CC(C)C1CCC(CC1)N1CCC(CC1)N1c2ccccc2CN(CC#N)S1(=O)=O |(1.34,-9.03,;-.02,-8.25,;-1.35,-9.05,;-.04,-6.71,;-1.37,-5.95,;-1.37,-4.4,;-.04,-3.62,;1.29,-4.4,;1.29,-5.95,;-.04,-2.07,;-1.39,-1.36,;-1.43,.21,;-.11,1.01,;1.25,.27,;1.27,-1.29,;-.14,2.55,;-1.49,3.27,;-2.8,2.46,;-4.13,3.2,;-4.18,4.75,;-2.87,5.54,;-1.51,4.79,;-.23,5.6,;1.13,4.86,;2.44,5.67,;3.8,4.95,;5.14,4.19,;1.17,3.34,;2.65,3.74,;1.57,1.85,)| Show InChI InChI=1S/C23H34N4O2S/c1-18(2)19-7-9-21(10-8-19)25-14-11-22(12-15-25)27-23-6-4-3-5-20(23)17-26(16-13-24)30(27,28)29/h3-6,18-19,21-22H,7-12,14-17H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue Pharma LP
Curated by ChEMBL
| Assay Description Inhibition of [3H]naltrindole binding to human Opioid receptor delta 1 |
Bioorg Med Chem Lett 14: 5045-50 (2004)
Article DOI: 10.1016/j.bmcl.2004.08.001 BindingDB Entry DOI: 10.7270/Q2TM7BV8 |
More data for this Ligand-Target Pair | |
Nociceptin receptor
(Homo sapiens (Human)) | BDBM50153131
(CHEMBL185415 | {1-[1-(4-Isopropyl-cyclohexyl)-pipe...)Show SMILES CC(C)C1CCC(CC1)N1CCC(CC1)N1c2ccccc2CN(CC#N)S1(=O)=O |(1.34,-9.03,;-.02,-8.25,;-1.35,-9.05,;-.04,-6.71,;-1.37,-5.95,;-1.37,-4.4,;-.04,-3.62,;1.29,-4.4,;1.29,-5.95,;-.04,-2.07,;-1.39,-1.36,;-1.43,.21,;-.11,1.01,;1.25,.27,;1.27,-1.29,;-.14,2.55,;-1.49,3.27,;-2.8,2.46,;-4.13,3.2,;-4.18,4.75,;-2.87,5.54,;-1.51,4.79,;-.23,5.6,;1.13,4.86,;2.44,5.67,;3.8,4.95,;5.14,4.19,;1.17,3.34,;2.65,3.74,;1.57,1.85,)| Show InChI InChI=1S/C23H34N4O2S/c1-18(2)19-7-9-21(10-8-19)25-14-11-22(12-15-25)27-23-6-4-3-5-20(23)17-26(16-13-24)30(27,28)29/h3-6,18-19,21-22H,7-12,14-17H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 227 | n/a | n/a | n/a | n/a |
Purdue Pharma LP
Curated by ChEMBL
| Assay Description Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor like 1 |
Bioorg Med Chem Lett 14: 5045-50 (2004)
Article DOI: 10.1016/j.bmcl.2004.08.001 BindingDB Entry DOI: 10.7270/Q2TM7BV8 |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50153131
(CHEMBL185415 | {1-[1-(4-Isopropyl-cyclohexyl)-pipe...)Show SMILES CC(C)C1CCC(CC1)N1CCC(CC1)N1c2ccccc2CN(CC#N)S1(=O)=O |(1.34,-9.03,;-.02,-8.25,;-1.35,-9.05,;-.04,-6.71,;-1.37,-5.95,;-1.37,-4.4,;-.04,-3.62,;1.29,-4.4,;1.29,-5.95,;-.04,-2.07,;-1.39,-1.36,;-1.43,.21,;-.11,1.01,;1.25,.27,;1.27,-1.29,;-.14,2.55,;-1.49,3.27,;-2.8,2.46,;-4.13,3.2,;-4.18,4.75,;-2.87,5.54,;-1.51,4.79,;-.23,5.6,;1.13,4.86,;2.44,5.67,;3.8,4.95,;5.14,4.19,;1.17,3.34,;2.65,3.74,;1.57,1.85,)| Show InChI InChI=1S/C23H34N4O2S/c1-18(2)19-7-9-21(10-8-19)25-14-11-22(12-15-25)27-23-6-4-3-5-20(23)17-26(16-13-24)30(27,28)29/h3-6,18-19,21-22H,7-12,14-17H2,1-2H3 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 344 | n/a | n/a | n/a | n/a |
Purdue Pharma LP
Curated by ChEMBL
| Assay Description Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor mu 1 |
Bioorg Med Chem Lett 14: 5045-50 (2004)
Article DOI: 10.1016/j.bmcl.2004.08.001 BindingDB Entry DOI: 10.7270/Q2TM7BV8 |
More data for this Ligand-Target Pair | |