Found 6 hits for monomerid = 50153135 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50153135
(1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-3,4-dih...)Show SMILES O=S1(=O)NCc2ccccc2N1C1CCN(CCC(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C27H31N3O2S/c31-33(32)28-21-24-13-7-8-14-27(24)30(33)25-15-18-29(19-16-25)20-17-26(22-9-3-1-4-10-22)23-11-5-2-6-12-23/h1-14,25-26,28H,15-21H2 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue Pharma LP
Curated by ChEMBL
| Assay Description Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1 |
Bioorg Med Chem Lett 14: 5045-50 (2004)
Article DOI: 10.1016/j.bmcl.2004.08.001 BindingDB Entry DOI: 10.7270/Q2TM7BV8 |
More data for this Ligand-Target Pair | |
Nociceptin receptor
(Homo sapiens (Human)) | BDBM50153135
(1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-3,4-dih...)Show SMILES O=S1(=O)NCc2ccccc2N1C1CCN(CCC(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C27H31N3O2S/c31-33(32)28-21-24-13-7-8-14-27(24)30(33)25-15-18-29(19-16-25)20-17-26(22-9-3-1-4-10-22)23-11-5-2-6-12-23/h1-14,25-26,28H,15-21H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 83 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue Pharma LP
Curated by ChEMBL
| Assay Description Inhibition of [3H]nociceptin binding to human Opioid receptor like 1 |
Bioorg Med Chem Lett 14: 5045-50 (2004)
Article DOI: 10.1016/j.bmcl.2004.08.001 BindingDB Entry DOI: 10.7270/Q2TM7BV8 |
More data for this Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50153135
(1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-3,4-dih...)Show SMILES O=S1(=O)NCc2ccccc2N1C1CCN(CCC(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C27H31N3O2S/c31-33(32)28-21-24-13-7-8-14-27(24)30(33)25-15-18-29(19-16-25)20-17-26(22-9-3-1-4-10-22)23-11-5-2-6-12-23/h1-14,25-26,28H,15-21H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue Pharma LP
Curated by ChEMBL
| Assay Description Inhibition of [3H]U-69593 binding to human Opioid receptor kappa 1 |
Bioorg Med Chem Lett 14: 5045-50 (2004)
Article DOI: 10.1016/j.bmcl.2004.08.001 BindingDB Entry DOI: 10.7270/Q2TM7BV8 |
More data for this Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50153135
(1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-3,4-dih...)Show SMILES O=S1(=O)NCc2ccccc2N1C1CCN(CCC(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C27H31N3O2S/c31-33(32)28-21-24-13-7-8-14-27(24)30(33)25-15-18-29(19-16-25)20-17-26(22-9-3-1-4-10-22)23-11-5-2-6-12-23/h1-14,25-26,28H,15-21H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue Pharma LP
Curated by ChEMBL
| Assay Description Inhibition of [3H]naltrindole binding to human Opioid receptor delta 1 |
Bioorg Med Chem Lett 14: 5045-50 (2004)
Article DOI: 10.1016/j.bmcl.2004.08.001 BindingDB Entry DOI: 10.7270/Q2TM7BV8 |
More data for this Ligand-Target Pair | |
Nociceptin receptor
(Homo sapiens (Human)) | BDBM50153135
(1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-3,4-dih...)Show SMILES O=S1(=O)NCc2ccccc2N1C1CCN(CCC(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C27H31N3O2S/c31-33(32)28-21-24-13-7-8-14-27(24)30(33)25-15-18-29(19-16-25)20-17-26(22-9-3-1-4-10-22)23-11-5-2-6-12-23/h1-14,25-26,28H,15-21H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.65E+3 | n/a | n/a | n/a | n/a |
Purdue Pharma LP
Curated by ChEMBL
| Assay Description Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor like 1 |
Bioorg Med Chem Lett 14: 5045-50 (2004)
Article DOI: 10.1016/j.bmcl.2004.08.001 BindingDB Entry DOI: 10.7270/Q2TM7BV8 |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50153135
(1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-3,4-dih...)Show SMILES O=S1(=O)NCc2ccccc2N1C1CCN(CCC(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C27H31N3O2S/c31-33(32)28-21-24-13-7-8-14-27(24)30(33)25-15-18-29(19-16-25)20-17-26(22-9-3-1-4-10-22)23-11-5-2-6-12-23/h1-14,25-26,28H,15-21H2 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 801 | n/a | n/a | n/a | n/a |
Purdue Pharma LP
Curated by ChEMBL
| Assay Description Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor mu 1 |
Bioorg Med Chem Lett 14: 5045-50 (2004)
Article DOI: 10.1016/j.bmcl.2004.08.001 BindingDB Entry DOI: 10.7270/Q2TM7BV8 |
More data for this Ligand-Target Pair | |