BDBM50153136 1-(1-Biphenyl-4-ylmethyl-piperidin-4-yl)-3,4-dihydro-1H-benzo[1,2,6]thiadiazine 2,2-dioxide::CHEMBL187907

SMILES: O=S1(=O)NCc2ccccc2N1C1CCN(Cc2ccc(cc2)-c2ccccc2)CC1

InChI Key: InChIKey=HBVGJIDEXACOHV-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50153136   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50153136 (1-(1-Biphenyl-4-ylmethyl-piperidin-4-yl)-3,4-dihyd...) Show SMILES O=S1(=O)NCc2ccccc2N1C1CCN(Cc2ccc(cc2)-c2ccccc2)CC1 Show InChI InChI=1S/C25H27N3O2S/c29-31(30)26-18-23-8-4-5-9-25(23)28(31)24-14-16-27(17-15-24)19-20-10-12-22(13-11-20)21-6-2-1-3-7-21/h1-13,24,26H,14-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma LP Curated by ChEMBL					Assay Description Inhibition of [3H]naltrindole binding to human Opioid receptor delta 1				Bioorg Med Chem Lett 14: 5045-50 (2004) Article DOI: 10.1016/j.bmcl.2004.08.001 BindingDB Entry DOI: 10.7270/Q2TM7BV8
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50153136 (1-(1-Biphenyl-4-ylmethyl-piperidin-4-yl)-3,4-dihyd...) Show SMILES O=S1(=O)NCc2ccccc2N1C1CCN(Cc2ccc(cc2)-c2ccccc2)CC1 Show InChI InChI=1S/C25H27N3O2S/c29-31(30)26-18-23-8-4-5-9-25(23)28(31)24-14-16-27(17-15-24)19-20-10-12-22(13-11-20)21-6-2-1-3-7-21/h1-13,24,26H,14-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma LP Curated by ChEMBL					Assay Description Inhibition of [3H]U-69593 binding to human Opioid receptor kappa 1				Bioorg Med Chem Lett 14: 5045-50 (2004) Article DOI: 10.1016/j.bmcl.2004.08.001 BindingDB Entry DOI: 10.7270/Q2TM7BV8
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50153136 (1-(1-Biphenyl-4-ylmethyl-piperidin-4-yl)-3,4-dihyd...) Show SMILES O=S1(=O)NCc2ccccc2N1C1CCN(Cc2ccc(cc2)-c2ccccc2)CC1 Show InChI InChI=1S/C25H27N3O2S/c29-31(30)26-18-23-8-4-5-9-25(23)28(31)24-14-16-27(17-15-24)19-20-10-12-22(13-11-20)21-6-2-1-3-7-21/h1-13,24,26H,14-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.54E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma LP Curated by ChEMBL					Assay Description Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor like 1				Bioorg Med Chem Lett 14: 5045-50 (2004) Article DOI: 10.1016/j.bmcl.2004.08.001 BindingDB Entry DOI: 10.7270/Q2TM7BV8
					More data for this Ligand-Target Pair