BDBM50153165 6-(((1-(4-cyanobenzyl)-1H-imidazol-5-yl)methoxy)methyl)-4'-ethoxybiphenyl-3-carbonitrile::6-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethoxymethyl]-4''-ethoxy-biphenyl-3-carbonitrile::CHEMBL184568

SMILES: CCOc1ccc(cc1)-c1cc(ccc1COCc1cncn1Cc1ccc(cc1)C#N)C#N

InChI Key: InChIKey=GRKGCIUUSLKRTB-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50153165   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) Chain B (Homo sapiens (Human))	BDBM50153165 (6-(((1-(4-cyanobenzyl)-1H-imidazol-5-yl)methoxy)me...) Show SMILES CCOc1ccc(cc1)-c1cc(ccc1COCc1cncn1Cc1ccc(cc1)C#N)C#N Show InChI InChI=1S/C28H24N4O2/c1-2-34-27-11-9-24(10-12-27)28-13-23(15-30)7-8-25(28)18-33-19-26-16-31-20-32(26)17-22-5-3-21(14-29)4-6-22/h3-13,16,20H,2,17-19H2,1H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-FPP incorporation into recombinant Ras CVIM by human Farnesyltransferase				Bioorg Med Chem Lett 14: 5057-62 (2004) Article DOI: 10.1016/j.bmcl.2004.07.083 BindingDB Entry DOI: 10.7270/Q2N0160C
					More data for this Ligand-Target Pair
Protein Farnesyltransferase (PFT) (Bos taurus (bovine))	BDBM50153165 (6-(((1-(4-cyanobenzyl)-1H-imidazol-5-yl)methoxy)me...) Show SMILES CCOc1ccc(cc1)-c1cc(ccc1COCc1cncn1Cc1ccc(cc1)C#N)C#N Show InChI InChI=1S/C28H24N4O2/c1-2-34-27-11-9-24(10-12-27)28-13-23(15-30)7-8-25(28)18-33-19-26-16-31-20-32(26)17-22-5-3-21(14-29)4-6-22/h3-13,16,20H,2,17-19H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of bovine farnesyltransferase				Bioorg Med Chem Lett 14: 5371-6 (2004) Article DOI: 10.1016/j.bmcl.2004.08.011 BindingDB Entry DOI: 10.7270/Q2J102N8
					More data for this Ligand-Target Pair
Geranylgeranyl Transferase (GGTase-I) (Bos taurus (bovine))	BDBM50153165 (6-(((1-(4-cyanobenzyl)-1H-imidazol-5-yl)methoxy)me...) Show SMILES CCOc1ccc(cc1)-c1cc(ccc1COCc1cncn1Cc1ccc(cc1)C#N)C#N Show InChI InChI=1S/C28H24N4O2/c1-2-34-27-11-9-24(10-12-27)28-13-23(15-30)7-8-25(28)18-33-19-26-16-31-20-32(26)17-22-5-3-21(14-29)4-6-22/h3-13,16,20H,2,17-19H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of bovine Geranylgeranyltransferase				Bioorg Med Chem Lett 14: 5371-6 (2004) Article DOI: 10.1016/j.bmcl.2004.08.011 BindingDB Entry DOI: 10.7270/Q2J102N8
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type I beta subunit/Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50153165 (6-(((1-(4-cyanobenzyl)-1H-imidazol-5-yl)methoxy)me...) Show SMILES CCOc1ccc(cc1)-c1cc(ccc1COCc1cncn1Cc1ccc(cc1)C#N)C#N Show InChI InChI=1S/C28H24N4O2/c1-2-34-27-11-9-24(10-12-27)28-13-23(15-30)7-8-25(28)18-33-19-26-16-31-20-32(26)17-22-5-3-21(14-29)4-6-22/h3-13,16,20H,2,17-19H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-GGPP incorporation into C-terminus of K-Ras by human Geranylgeranyl transferase type I				Bioorg Med Chem Lett 14: 5057-62 (2004) Article DOI: 10.1016/j.bmcl.2004.07.083 BindingDB Entry DOI: 10.7270/Q2N0160C
					More data for this Ligand-Target Pair