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SMILES: FC(F)(F)CNC(=O)C1(CCCCP2(=O)OCC(CO2)NC(=O)c2ccccc2-c2nc3ccccc3o2)c2ccccc2-c2ccccc12

InChI Key: InChIKey=YMMMGJDZLXSXLS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50153193   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Microsomal triglyceride transfer protein large subunit


(Homo sapiens (Human))		BDBM50153193
PNG
(CHEMBL186836 | Trans-9-{4-[5-(2-Benzooxazol-2-yl-b...)
Show SMILES FC(F)(F)CNC(=O)C1(CCCCP2(=O)OCC(CO2)NC(=O)c2ccccc2-c2nc3ccccc3o2)c2ccccc2-c2ccccc12
Show InChI InChI=1S/C37H33F3N3O6P/c38-37(39,40)23-41-35(45)36(29-15-5-3-11-25(29)26-12-4-6-16-30(26)36)19-9-10-20-50(46)47-21-24(22-48-50)42-33(44)27-13-1-2-14-28(27)34-43-31-17-7-8-18-32(31)49-34/h1-8,11-18,24H,9-10,19-23H2,(H,41,45)(H,42,44)
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n/an/a 3n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against human Microsomal triglyceride transfer protein

Bioorg Med Chem Lett 14: 5067-70 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.069
BindingDB Entry DOI: 10.7270/Q2H70F93
More data for this
Ligand-Target Pair