null

SMILES: Cc1cccc(NC(=O)CN2CCN(CC2)c2ccc(cc2)C(c2ccccc2)c2ccccc2)c1

InChI Key: InChIKey=NZNYRZNCHUMSCE-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153256   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50153256 (2-[4-(4-Benzhydryl-phenyl)-piperazin-1-yl]-N-m-tol...) Show SMILES Cc1cccc(NC(=O)CN2CCN(CC2)c2ccc(cc2)C(c2ccccc2)c2ccccc2)c1 Show InChI InChI=1S/C32H33N3O/c1-25-9-8-14-29(23-25)33-31(36)24-34-19-21-35(22-20-34)30-17-15-28(16-18-30)32(26-10-4-2-5-11-26)27-12-6-3-7-13-27/h2-18,23,32H,19-22,24H2,1H3,(H,33,36)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	175	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro ability to inhibit [3H]-6b binding to human Dopamine receptor D4.4				Bioorg Med Chem Lett 14: 5095-8 (2004) Article DOI: 10.1016/j.bmcl.2004.07.068 BindingDB Entry DOI: 10.7270/Q23X863Q
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50153256 (2-[4-(4-Benzhydryl-phenyl)-piperazin-1-yl]-N-m-tol...) Show SMILES Cc1cccc(NC(=O)CN2CCN(CC2)c2ccc(cc2)C(c2ccccc2)c2ccccc2)c1 Show InChI InChI=1S/C32H33N3O/c1-25-9-8-14-29(23-25)33-31(36)24-34-19-21-35(22-20-34)30-17-15-28(16-18-30)32(26-10-4-2-5-11-26)27-12-6-3-7-13-27/h2-18,23,32H,19-22,24H2,1H3,(H,33,36)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Agonist activity was calculated in calcium flux assay using HEK-293 cells co-transfected with human Dopamine receptor D4.4 and Galphaqo5				Bioorg Med Chem Lett 14: 5095-8 (2004) Article DOI: 10.1016/j.bmcl.2004.07.068 BindingDB Entry DOI: 10.7270/Q23X863Q
					More data for this Ligand-Target Pair