null

SMILES: Cc1cccc(NC(=O)CN2CCN(CC2)c2ccc(cc2)-c2ccccc2)c1

InChI Key: InChIKey=DULALBWPOFGOBM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153258   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50153258 (2-(4-Biphenyl-4-yl-piperazin-1-yl)-N-m-tolyl-aceta...) Show SMILES Cc1cccc(NC(=O)CN2CCN(CC2)c2ccc(cc2)-c2ccccc2)c1 Show InChI InChI=1S/C25H27N3O/c1-20-6-5-9-23(18-20)26-25(29)19-27-14-16-28(17-15-27)24-12-10-22(11-13-24)21-7-3-2-4-8-21/h2-13,18H,14-17,19H2,1H3,(H,26,29)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro ability to inhibit [3H]-6b binding to human Dopamine receptor D4.4				Bioorg Med Chem Lett 14: 5095-8 (2004) Article DOI: 10.1016/j.bmcl.2004.07.068 BindingDB Entry DOI: 10.7270/Q23X863Q
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50153258 (2-(4-Biphenyl-4-yl-piperazin-1-yl)-N-m-tolyl-aceta...) Show SMILES Cc1cccc(NC(=O)CN2CCN(CC2)c2ccc(cc2)-c2ccccc2)c1 Show InChI InChI=1S/C25H27N3O/c1-20-6-5-9-23(18-20)26-25(29)19-27-14-16-28(17-15-27)24-12-10-22(11-13-24)21-7-3-2-4-8-21/h2-13,18H,14-17,19H2,1H3,(H,26,29)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Agonist activity was calculated in calcium flux assay using HEK-293 cells co-transfected with human Dopamine receptor D4.4 and Galphaqo5				Bioorg Med Chem Lett 14: 5095-8 (2004) Article DOI: 10.1016/j.bmcl.2004.07.068 BindingDB Entry DOI: 10.7270/Q23X863Q
					More data for this Ligand-Target Pair