null

SMILES: Cc1cccc(NC(=O)CN2CCN(CC2)c2ccncc2)c1

InChI Key: InChIKey=JVUKJJSDYTTXPN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50153262   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50153262 (2-(4-Pyridin-4-yl-piperazin-1-yl)-N-m-tolyl-acetam...) Show SMILES Cc1cccc(NC(=O)CN2CCN(CC2)c2ccncc2)c1 Show InChI InChI=1S/C18H22N4O/c1-15-3-2-4-16(13-15)20-18(23)14-21-9-11-22(12-10-21)17-5-7-19-8-6-17/h2-8,13H,9-12,14H2,1H3,(H,20,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro ability to inhibit [3H]-spiperone binding to human Dopamine receptor D4.4				Bioorg Med Chem Lett 14: 5095-8 (2004) Article DOI: 10.1016/j.bmcl.2004.07.068 BindingDB Entry DOI: 10.7270/Q23X863Q
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50153262 (2-(4-Pyridin-4-yl-piperazin-1-yl)-N-m-tolyl-acetam...) Show SMILES Cc1cccc(NC(=O)CN2CCN(CC2)c2ccncc2)c1 Show InChI InChI=1S/C18H22N4O/c1-15-3-2-4-16(13-15)20-18(23)14-21-9-11-22(12-10-21)17-5-7-19-8-6-17/h2-8,13H,9-12,14H2,1H3,(H,20,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro ability to inhibit [3H]-6b binding to human Dopamine receptor D4.4				Bioorg Med Chem Lett 14: 5095-8 (2004) Article DOI: 10.1016/j.bmcl.2004.07.068 BindingDB Entry DOI: 10.7270/Q23X863Q
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50153262 (2-(4-Pyridin-4-yl-piperazin-1-yl)-N-m-tolyl-acetam...) Show SMILES Cc1cccc(NC(=O)CN2CCN(CC2)c2ccncc2)c1 Show InChI InChI=1S/C18H22N4O/c1-15-3-2-4-16(13-15)20-18(23)14-21-9-11-22(12-10-21)17-5-7-19-8-6-17/h2-8,13H,9-12,14H2,1H3,(H,20,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Agonist activity was calculated in calcium flux assay using HEK-293 cells co-transfected with human Dopamine receptor D4.4 and Galphaqo5				Bioorg Med Chem Lett 14: 5095-8 (2004) Article DOI: 10.1016/j.bmcl.2004.07.068 BindingDB Entry DOI: 10.7270/Q23X863Q
					More data for this Ligand-Target Pair