BDBM50153288 CHEMBL3775693

SMILES: CCOC(=O)c1c(C)n(Cc2ccccc2)c2ccc(OCC(N)CO)cc12

InChI Key: InChIKey=MUFUIHUSGVASCG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50153288   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Quinolone resistance protein norA (Staphylococcus aureus)	BDBM50153288 (CHEMBL3775693) Show SMILES CCOC(=O)c1c(C)n(Cc2ccccc2)c2ccc(OCC(N)CO)cc12 Show InChI InChI=1S/C22H26N2O4/c1-3-27-22(26)21-15(2)24(12-16-7-5-4-6-8-16)20-10-9-18(11-19(20)21)28-14-17(23)13-25/h4-11,17,25H,3,12-14,23H2,1-2H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Perugia Curated by ChEMBL					Assay Description Inhibition of NorA efflux pump in Staphylococcus aureus 1199B assessed as reduction in EtBr efflux incubated for 20 mins measured for 5 mins by real-...				J Med Chem 59: 867-91 (2016) BindingDB Entry DOI: 10.7270/Q28W3G57
					More data for this Ligand-Target Pair