BDBM50153302 3-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-1-[2-hydroxy-4-methyl-6-(3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-phenyl]-propan-1-one::CHEMBL187163
SMILES: Cc1cc(O)c(C(=O)CCc2ccc3OCCOc3c2)c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1
InChI Key: InChIKey=IINBYKILNZBSAK-PFKOEMKTSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium/glucose cotransporter 2 (Homo sapiens (Human)) | BDBM50153302 (3-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-1-[2-hydroxy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 2 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/glucose cotransporter 1 (SGLT1) (Homo sapiens (Human)) | BDBM50153302 (3-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-1-[2-hydroxy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of Na-dependent [14C]-AMG uptake in CHO-K1 cells expressing human sodium glucose co-transporter 1 | Bioorg Med Chem Lett 14: 5121-5 (2004) Article DOI: 10.1016/j.bmcl.2004.07.082 BindingDB Entry DOI: 10.7270/Q2VD6XX2 | |||||||||||
More data for this Ligand-Target Pair |