BDBM50153325 CHEMBL3774487

SMILES: Cc1ccc(C)c(CNc2cnccc2C(O)=O)c1

InChI Key: InChIKey=SHPWWCBOQVRBIG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153325   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM50153325 (CHEMBL3774487) Show SMILES Cc1ccc(C)c(CNc2cnccc2C(O)=O)c1 Show InChI InChI=1S/C15H16N2O2/c1-10-3-4-11(2)12(7-10)8-17-14-9-16-6-5-13(14)15(18)19/h3-7,9,17H,8H2,1-2H3,(H,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of KDM4C (unknown origin) using H3K9Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire mass spectrometric analys...				J Med Chem 59: 1357-69 (2016) BindingDB Entry DOI: 10.7270/Q2542QFT
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM50153325 (CHEMBL3774487) Show SMILES Cc1ccc(C)c(CNc2cnccc2C(O)=O)c1 Show InChI InChI=1S/C15H16N2O2/c1-10-3-4-11(2)12(7-10)8-17-14-9-16-6-5-13(14)15(18)19/h3-7,9,17H,8H2,1-2H3,(H,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of full length human HALO-tagged KDM4C expressed in human U2OS cells assessed as level of H3K9Me3 demethylation incubated overnight by Hoe...				J Med Chem 59: 1357-69 (2016) BindingDB Entry DOI: 10.7270/Q2542QFT
					More data for this Ligand-Target Pair