BDBM50153327 CHEMBL3775151

SMILES: OC(=O)c1ccncc1NCc1cccc(c1)-c1ccccc1

InChI Key: InChIKey=ILCCZYRMKZNNSG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153327   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM50153327 (CHEMBL3775151) Show SMILES OC(=O)c1ccncc1NCc1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C19H16N2O2/c22-19(23)17-9-10-20-13-18(17)21-12-14-5-4-8-16(11-14)15-6-2-1-3-7-15/h1-11,13,21H,12H2,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of KDM4C (unknown origin) using H3K9Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire mass spectrometric analys...				J Med Chem 59: 1357-69 (2016) BindingDB Entry DOI: 10.7270/Q2542QFT
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM50153327 (CHEMBL3775151) Show SMILES OC(=O)c1ccncc1NCc1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C19H16N2O2/c22-19(23)17-9-10-20-13-18(17)21-12-14-5-4-8-16(11-14)15-6-2-1-3-7-15/h1-11,13,21H,12H2,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of full length human HALO-tagged KDM4C expressed in human U2OS cells assessed as level of H3K9Me3 demethylation incubated overnight by Hoe...				J Med Chem 59: 1357-69 (2016) BindingDB Entry DOI: 10.7270/Q2542QFT
					More data for this Ligand-Target Pair