BDBM50153522 2-(2-Fluoro-ethoxy)-4-{[(S)-3-methyl-1-(2-piperidin-1-yl-phenyl)-butylcarbamoyl]-methyl}-benzoic acid::CHEMBL186684
SMILES: CC(C)C[C@H](NC(=O)Cc1ccc(C(O)=O)c(OCCF)c1)c1ccccc1N1CCCCC1
InChI Key: InChIKey=SOUVIYRQMIWZAJ-QHCPKHFHSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Sulfonylurea receptor 1 (Homo sapiens (Human)) | BDBM50153522 (2-(2-Fluoro-ethoxy)-4-{[(S)-3-methyl-1-(2-piperidi...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 134 | n/a | n/a | n/a | n/a | n/a |
University of Mainz Curated by ChEMBL | Assay Description Displacement of [3H]glibenclamide from COS-1 cells expressing Sulfonylurea receptor 1 (SUR-1) | Bioorg Med Chem Lett 14: 5205-9 (2004) Article DOI: 10.1016/j.bmcl.2004.07.059 BindingDB Entry DOI: 10.7270/Q2BG2NGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sulfonylurea receptor 1 (Homo sapiens (Human)) | BDBM50153522 (2-(2-Fluoro-ethoxy)-4-{[(S)-3-methyl-1-(2-piperidi...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 281 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Mainz Curated by ChEMBL | Assay Description In vitro displacement of [3H]-glibenclamide (IC50=0.61) from COS-1 cells expressing Sulfonylurea receptor 1 (SUR-1) | Bioorg Med Chem Lett 14: 5205-9 (2004) Article DOI: 10.1016/j.bmcl.2004.07.059 BindingDB Entry DOI: 10.7270/Q2BG2NGF | |||||||||||
More data for this Ligand-Target Pair |