BDBM50153569 3-Naphthalen-2-yl-4-[1-(3-5,6,7,8-tetrahydro-[1,8]naphthyridin-2-yl-propionyl)-piperidin-4-yl]-butyric acid::CHEMBL365272

SMILES: OC(=O)CC(CC1CCN(CC1)C(=O)CCc1ccc2CCCNc2n1)c1ccc2ccccc2c1

InChI Key: InChIKey=MDGSJXNNVZDXCV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153569   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ITGAV/ITGB3 (Homo sapiens (Human))	BDBM50153569 (3-Naphthalen-2-yl-4-[1-(3-5,6,7,8-tetrahydro-[1,8]...) Show SMILES OC(=O)CC(CC1CCN(CC1)C(=O)CCc1ccc2CCCNc2n1)c1ccc2ccccc2c1 Show InChI InChI=1S/C30H35N3O3/c34-28(12-11-27-10-9-23-6-3-15-31-30(23)32-27)33-16-13-21(14-17-33)18-26(20-29(35)36)25-8-7-22-4-1-2-5-24(22)19-25/h1-2,4-5,7-10,19,21,26H,3,6,11-18,20H2,(H,31,32)(H,35,36)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human vitronectin binding to immobilized Alpha v beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50153569 (3-Naphthalen-2-yl-4-[1-(3-5,6,7,8-tetrahydro-[1,8]...) Show SMILES OC(=O)CC(CC1CCN(CC1)C(=O)CCc1ccc2CCCNc2n1)c1ccc2ccccc2c1 Show InChI InChI=1S/C30H35N3O3/c34-28(12-11-27-10-9-23-6-3-15-31-30(23)32-27)33-16-13-21(14-17-33)18-26(20-29(35)36)25-8-7-22-4-1-2-5-24(22)19-25/h1-2,4-5,7-10,19,21,26H,3,6,11-18,20H2,(H,31,32)(H,35,36)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Biotinylated Fg binding to immobilized Alpha II beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair