BDBM50153605 CHEMBL3774702

SMILES: CCn1c(CCC(=O)Nc2cccc3ccccc23)nnc1CC1CCCCC1

InChI Key: InChIKey=SKBYTIIASSTFHO-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153605   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (Mus musculus)	BDBM50153605 (CHEMBL3774702) Show SMILES CCn1c(CCC(=O)Nc2cccc3ccccc23)nnc1CC1CCCCC1 Show InChI InChI=1S/C24H30N4O/c1-2-28-22(26-27-23(28)17-18-9-4-3-5-10-18)15-16-24(29)25-21-14-8-12-19-11-6-7-13-20(19)21/h6-8,11-14,18H,2-5,9-10,15-17H2,1H3,(H,25,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...				ACS Med Chem Lett 7: 23-7 (2016) BindingDB Entry DOI: 10.7270/Q2N58P7P
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (RORC) (Homo sapiens (Human))	BDBM50153605 (CHEMBL3774702) Show SMILES CCn1c(CCC(=O)Nc2cccc3ccccc23)nnc1CC1CCCCC1 Show InChI InChI=1S/C24H30N4O/c1-2-28-22(26-27-23(28)17-18-9-4-3-5-10-18)15-16-24(29)25-21-14-8-12-19-11-6-7-13-20(19)21/h6-8,11-14,18H,2-5,9-10,15-17H2,1H3,(H,25,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human RORgamma ligand binding domain (Serine 253 to Lysine 518 residues) expressed in CHOK1 cells incubated for 2 days by Gal4 lucifera...				ACS Med Chem Lett 7: 23-7 (2016) BindingDB Entry DOI: 10.7270/Q2N58P7P
					More data for this Ligand-Target Pair