BDBM50153649 CHEMBL3775324

SMILES: Cc1ccc(NC(=O)CCc2nnc(CCC3CCCCC3)n2C2CCC2)c(C)c1

InChI Key: InChIKey=MWJNLALSLLUFEE-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153649   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (Mus musculus)	BDBM50153649 (CHEMBL3775324) Show SMILES Cc1ccc(NC(=O)CCc2nnc(CCC3CCCCC3)n2C2CCC2)c(C)c1 Show InChI InChI=1S/C25H36N4O/c1-18-11-13-22(19(2)17-18)26-25(30)16-15-24-28-27-23(29(24)21-9-6-10-21)14-12-20-7-4-3-5-8-20/h11,13,17,20-21H,3-10,12,14-16H2,1-2H3,(H,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...				ACS Med Chem Lett 7: 23-7 (2016) BindingDB Entry DOI: 10.7270/Q2N58P7P
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (RORC) (Homo sapiens (Human))	BDBM50153649 (CHEMBL3775324) Show SMILES Cc1ccc(NC(=O)CCc2nnc(CCC3CCCCC3)n2C2CCC2)c(C)c1 Show InChI InChI=1S/C25H36N4O/c1-18-11-13-22(19(2)17-18)26-25(30)16-15-24-28-27-23(29(24)21-9-6-10-21)14-12-20-7-4-3-5-8-20/h11,13,17,20-21H,3-10,12,14-16H2,1-2H3,(H,26,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human RORgamma ligand binding domain (Serine 253 to Lysine 518 residues) expressed in CHOK1 cells incubated for 2 days by Gal4 lucifera...				ACS Med Chem Lett 7: 23-7 (2016) BindingDB Entry DOI: 10.7270/Q2N58P7P
					More data for this Ligand-Target Pair