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SMILES: CCCc1c(OCCCCN(C)c2ccc(cc2)-c2nnn[nH]2)ccc(C(C)=O)c1O

InChI Key: InChIKey=PJOFFBPNUHEFJJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50153742   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))		BDBM50153742
PNG
(1-[2-Hydroxy-4-(4-{methyl-[4-(2H-tetrazol-5-yl)-ph...)
Show SMILES CCCc1c(OCCCCN(C)c2ccc(cc2)-c2nnn[nH]2)ccc(C(C)=O)c1O
Show InChI InChI=1S/C23H29N5O3/c1-4-7-20-21(13-12-19(16(2)29)22(20)30)31-15-6-5-14-28(3)18-10-8-17(9-11-18)23-24-26-27-25-23/h8-13,30H,4-7,14-15H2,1-3H3,(H,24,25,26,27)
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Article
PubMed
n/an/an/an/a 2.01E+3n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Effective concentration for binding to human metabotropic glutamate receptor 2 as determined by GTPgammaS assay

Bioorg Med Chem Lett 14: 5329-32 (2004)


Article DOI: 10.1016/j.bmcl.2004.08.020
BindingDB Entry DOI: 10.7270/Q21Z43W0
More data for this
Ligand-Target Pair