null

SMILES: CC(C)CC(=O)c1ccc(OCCCCOc2ccc(cc2)-c2nnn[nH]2)c(C)c1O

InChI Key: InChIKey=SBNFEGOZCWQPAQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153752   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50153752 (1-(2-Hydroxy-3-methyl-4-{4-[4-(1H-tetrazol-5-yl)-p...) Show SMILES CC(C)CC(=O)c1ccc(OCCCCOc2ccc(cc2)-c2nnn[nH]2)c(C)c1O Show InChI InChI=1S/C23H28N4O4/c1-15(2)14-20(28)19-10-11-21(16(3)22(19)29)31-13-5-4-12-30-18-8-6-17(7-9-18)23-24-26-27-25-23/h6-11,15,29H,4-5,12-14H2,1-3H3,(H,24,25,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	229	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]-GTP gama S binding assay				Bioorg Med Chem Lett 14: 5867-72 (2004) Article DOI: 10.1016/j.bmcl.2004.09.028 BindingDB Entry DOI: 10.7270/Q2XW4J94
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50153752 (1-(2-Hydroxy-3-methyl-4-{4-[4-(1H-tetrazol-5-yl)-p...) Show SMILES CC(C)CC(=O)c1ccc(OCCCCOc2ccc(cc2)-c2nnn[nH]2)c(C)c1O Show InChI InChI=1S/C23H28N4O4/c1-15(2)14-20(28)19-10-11-21(16(3)22(19)29)31-13-5-4-12-30-18-8-6-17(7-9-18)23-24-26-27-25-23/h6-11,15,29H,4-5,12-14H2,1-3H3,(H,24,25,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	229	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for binding to human metabotropic glutamate receptor 2 as determined by GTPgammaS assay				Bioorg Med Chem Lett 14: 5329-32 (2004) Article DOI: 10.1016/j.bmcl.2004.08.020 BindingDB Entry DOI: 10.7270/Q21Z43W0
					More data for this Ligand-Target Pair