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SMILES: CC(C)CC(=O)c1ccc(OCCCCOc2ccc(cc2)-c2nnn[nH]2)c(Br)c1O

InChI Key: InChIKey=OGRBIYLJRMIQJY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50153756   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))		BDBM50153756
PNG
(1-(3-Bromo-2-hydroxy-4-{4-[4-(2H-tetrazol-5-yl)-ph...)
Show SMILES CC(C)CC(=O)c1ccc(OCCCCOc2ccc(cc2)-c2nnn[nH]2)c(Br)c1O
Show InChI InChI=1S/C22H25BrN4O4/c1-14(2)13-18(28)17-9-10-19(20(23)21(17)29)31-12-4-3-11-30-16-7-5-15(6-8-16)22-24-26-27-25-22/h5-10,14,29H,3-4,11-13H2,1-2H3,(H,24,25,26,27)
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Article
PubMed
n/an/an/an/a 93n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Effective concentration for binding to human metabotropic glutamate receptor 2 as determined by GTPgammaS assay

Bioorg Med Chem Lett 14: 5329-32 (2004)


Article DOI: 10.1016/j.bmcl.2004.08.020
BindingDB Entry DOI: 10.7270/Q21Z43W0
More data for this
Ligand-Target Pair