BDBM50153802 3'',4''-Dichloro-6-[3-(4-cyano-benzyl)-3H-imidazol-4-ylmethoxymethyl]-biphenyl-3-carbonitrile::3',4'-dichloro-6-(((1-(4-cyanobenzyl)-1H-imidazol-5-yl)methoxy)methyl)biphenyl-3-carbonitrile::CHEMBL187807

SMILES: Clc1ccc(cc1Cl)-c1cc(ccc1COCc1cncn1Cc1ccc(cc1)C#N)C#N

InChI Key: InChIKey=MREWDDFZIOFBSH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153802   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Geranylgeranyl Transferase (GGTase-I) (Bos taurus (bovine))	BDBM50153802 (3'',4''-Dichloro-6-[3-(4-cyano-benzyl)-3H-imidazol...) Show SMILES Clc1ccc(cc1Cl)-c1cc(ccc1COCc1cncn1Cc1ccc(cc1)C#N)C#N Show InChI InChI=1S/C26H18Cl2N4O/c27-25-8-7-21(10-26(25)28)24-9-20(12-30)5-6-22(24)15-33-16-23-13-31-17-32(23)14-19-3-1-18(11-29)2-4-19/h1-10,13,17H,14-16H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of bovine Geranylgeranyltransferase				Bioorg Med Chem Lett 14: 5371-6 (2004) Article DOI: 10.1016/j.bmcl.2004.08.011 BindingDB Entry DOI: 10.7270/Q2J102N8
					More data for this Ligand-Target Pair
Protein Farnesyltransferase (PFT) (Bos taurus (bovine))	BDBM50153802 (3'',4''-Dichloro-6-[3-(4-cyano-benzyl)-3H-imidazol...) Show SMILES Clc1ccc(cc1Cl)-c1cc(ccc1COCc1cncn1Cc1ccc(cc1)C#N)C#N Show InChI InChI=1S/C26H18Cl2N4O/c27-25-8-7-21(10-26(25)28)24-9-20(12-30)5-6-22(24)15-33-16-23-13-31-17-32(23)14-19-3-1-18(11-29)2-4-19/h1-10,13,17H,14-16H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.370	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of bovine farnesyltransferase				Bioorg Med Chem Lett 14: 5371-6 (2004) Article DOI: 10.1016/j.bmcl.2004.08.011 BindingDB Entry DOI: 10.7270/Q2J102N8
					More data for this Ligand-Target Pair