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SMILES: Cc1ccc(NC(=O)c2cc(F)cc(c2)N2CCOCC2)cc1NC(=O)c1ccc(OCc2cscn2)cc1

InChI Key: InChIKey=GOXPCWOINCMRAX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50153832   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50153832
PNG
(3-Fluoro-N-{4-methyl-3-[4-(thiazol-4-ylmethoxy)-be...)
Show SMILES Cc1ccc(NC(=O)c2cc(F)cc(c2)N2CCOCC2)cc1NC(=O)c1ccc(OCc2cscn2)cc1
Show InChI InChI=1S/C29H27FN4O4S/c1-19-2-5-23(32-29(36)21-12-22(30)14-25(13-21)34-8-10-37-11-9-34)15-27(19)33-28(35)20-3-6-26(7-4-20)38-16-24-17-39-18-31-24/h2-7,12-15,17-18H,8-11,16H2,1H3,(H,32,36)(H,33,35)
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n/an/a 10n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Concentration required to inhibit human mitogen activated protein kinase p38 activity

Bioorg Med Chem Lett 14: 5383-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.08.006
BindingDB Entry DOI: 10.7270/Q28G8K57
More data for this
Ligand-Target Pair