BDBM50154073 7-Allyl-2-(2-fluoro-4-hydroxy-phenyl)-benzooxazol-5-ol::7-allyl-2-(2-fluoro-4-hydroxyphenyl)benzo[d]oxazol-5-ol::CHEMBL189356

SMILES: Oc1ccc(-c2nc3cc(O)cc(CC=C)c3o2)c(F)c1

InChI Key: InChIKey=RFGHIDZADADSIN-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50154073   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estradiol receptor beta (ERβ) (Homo sapiens (Human))	BDBM50154073 (7-Allyl-2-(2-fluoro-4-hydroxy-phenyl)-benzooxazol-...) Show SMILES Oc1ccc(-c2nc3cc(O)cc(CC=C)c3o2)c(F)c1 Show InChI InChI=1S/C16H12FNO3/c1-2-3-9-6-11(20)8-14-15(9)21-16(18-14)12-5-4-10(19)7-13(12)17/h2,4-8,19-20H,1,3H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against human ER beta expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligand				J Med Chem 47: 5021-40 (2004) Article DOI: 10.1021/jm049719y BindingDB Entry DOI: 10.7270/Q2C828S5
					More data for this Ligand-Target Pair
Estradiol receptor beta (ERβ) (Homo sapiens (Human))	BDBM50154073 (7-Allyl-2-(2-fluoro-4-hydroxy-phenyl)-benzooxazol-...) Show SMILES Oc1ccc(-c2nc3cc(O)cc(CC=C)c3o2)c(F)c1 Show InChI InChI=1S/C16H12FNO3/c1-2-3-9-6-11(20)8-14-15(9)21-16(18-14)12-5-4-10(19)7-13(12)17/h2,4-8,19-20H,1,3H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Yantai University Curated by ChEMBL					Assay Description Binding affinity to ERbeta (unknown origin)				Eur J Med Chem 43: 43-52 (2008) Article DOI: 10.1016/j.ejmech.2007.03.002 BindingDB Entry DOI: 10.7270/Q2WD40BT
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50154073 (7-Allyl-2-(2-fluoro-4-hydroxy-phenyl)-benzooxazol-...) Show SMILES Oc1ccc(-c2nc3cc(O)cc(CC=C)c3o2)c(F)c1 Show InChI InChI=1S/C16H12FNO3/c1-2-3-9-6-11(20)8-14-15(9)21-16(18-14)12-5-4-10(19)7-13(12)17/h2,4-8,19-20H,1,3H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against human ER alpha expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligand				J Med Chem 47: 5021-40 (2004) Article DOI: 10.1021/jm049719y BindingDB Entry DOI: 10.7270/Q2C828S5
					More data for this Ligand-Target Pair