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BDBM50154209 8,8-Dimethyl-7-[methyl-((E)-3-phenyl-allyl)-amino]-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL365483

SMILES: CN(C\C=C\c1ccccc1)C1CCc2ccc(O)cc2C1(C)C

InChI Key: InChIKey=AHIRZFCBGSMDPL-JXMROGBWSA-N

Data: 3 KI

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50154209   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mu-type opioid receptor


(Homo sapiens (Human))
BDBM50154209
PNG
(8,8-Dimethyl-7-[methyl-((E)-3-phenyl-allyl)-amino]...)
Show SMILES CN(C\C=C\c1ccccc1)C1CCc2ccc(O)cc2C1(C)C
Show InChI InChI=1S/C22H27NO/c1-22(2)20-16-19(24)13-11-18(20)12-14-21(22)23(3)15-7-10-17-8-5-4-6-9-17/h4-11,13,16,21,24H,12,14-15H2,1-3H3/b10-7+
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
40n/an/an/an/an/an/an/an/a



University of Bath

Curated by ChEMBL


Assay Description
Inhibition of [3H]DAMGO binding to human Mu opioid receptor expressed in CHO cells


J Med Chem 47: 5069-75 (2004)


Article DOI: 10.1021/jm040807s
BindingDB Entry DOI: 10.7270/Q2S46SQB
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Homo sapiens (Human))
BDBM50154209
PNG
(8,8-Dimethyl-7-[methyl-((E)-3-phenyl-allyl)-amino]...)
Show SMILES CN(C\C=C\c1ccccc1)C1CCc2ccc(O)cc2C1(C)C
Show InChI InChI=1S/C22H27NO/c1-22(2)20-16-19(24)13-11-18(20)12-14-21(22)23(3)15-7-10-17-8-5-4-6-9-17/h4-11,13,16,21,24H,12,14-15H2,1-3H3/b10-7+
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PC sid
UniChem
Article
PubMed
207n/an/an/an/an/an/an/an/a



University of Bath

Curated by ChEMBL


Assay Description
Inhibition of [3H]U-69593 binding to human kappa opioid receptor expressed in CHO cells


J Med Chem 47: 5069-75 (2004)


Article DOI: 10.1021/jm040807s
BindingDB Entry DOI: 10.7270/Q2S46SQB
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Homo sapiens (Human))
BDBM50154209
PNG
(8,8-Dimethyl-7-[methyl-((E)-3-phenyl-allyl)-amino]...)
Show SMILES CN(C\C=C\c1ccccc1)C1CCc2ccc(O)cc2C1(C)C
Show InChI InChI=1S/C22H27NO/c1-22(2)20-16-19(24)13-11-18(20)12-14-21(22)23(3)15-7-10-17-8-5-4-6-9-17/h4-11,13,16,21,24H,12,14-15H2,1-3H3/b10-7+
PDB

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UniProtKB/SwissProt

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DrugBank
antibodypedia
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
591n/an/an/an/an/an/an/an/a



University of Bath

Curated by ChEMBL


Assay Description
Inhibition of [3H]C1-DPDPE binding to human delta opioid receptor expressed in CHO cells


J Med Chem 47: 5069-75 (2004)


Article DOI: 10.1021/jm040807s
BindingDB Entry DOI: 10.7270/Q2S46SQB
More data for this
Ligand-Target Pair