BDBM50154445 5-Hydroxy-2-(3-hydroxy-phenyl)-6-methoxy-pyrimidine-4-carboxylic acid::CHEMBL362571

SMILES: COc1nc(nc(C(O)=O)c1O)-c1cccc(O)c1

InChI Key: InChIKey=QGYWVGBIPCUSLL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50154445   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50154445 (5-Hydroxy-2-(3-hydroxy-phenyl)-6-methoxy-pyrimidin...) Show SMILES COc1nc(nc(C(O)=O)c1O)-c1cccc(O)c1 Show InChI InChI=1S/C12H10N2O5/c1-19-11-9(16)8(12(17)18)13-10(14-11)6-3-2-4-7(15)5-6/h2-5,15-16H,1H3,(H,17,18)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Italy. Vinc Curated by ChEMBL					Assay Description Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mn2+ is determined				J Med Chem 47: 5336-9 (2004) Article DOI: 10.1021/jm0494669 BindingDB Entry DOI: 10.7270/Q2G1609M
					More data for this Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50154445 (5-Hydroxy-2-(3-hydroxy-phenyl)-6-methoxy-pyrimidin...) Show SMILES COc1nc(nc(C(O)=O)c1O)-c1cccc(O)c1 Show InChI InChI=1S/C12H10N2O5/c1-19-11-9(16)8(12(17)18)13-10(14-11)6-3-2-4-7(15)5-6/h2-5,15-16H,1H3,(H,17,18)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Italy. Vinc Curated by ChEMBL					Assay Description Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mg2+ is determined				J Med Chem 47: 5336-9 (2004) Article DOI: 10.1021/jm0494669 BindingDB Entry DOI: 10.7270/Q2G1609M
					More data for this Ligand-Target Pair