BDBM50154476 (R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-(3-hydroxy-propane-1-sulfonyl)-3-methyl-1H-imidazo[1,2-a]imidazol-2-one::CHEMBL187820

SMILES: C[C@@]1(Cc2ccc(Br)cc2)C(=O)N(c2ncc(n12)S(=O)(=O)CCCO)c1cc(Cl)cc(Cl)c1

InChI Key: InChIKey=UQFJJELMTYQZLF-JOCHJYFZSA-N

Data: 3 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50154476   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-L/beta-2 (Homo sapiens (Human))	BDBM50154476 ((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-(...) Show SMILES C[C@@]1(Cc2ccc(Br)cc2)C(=O)N(c2ncc(n12)S(=O)(=O)CCCO)c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C22H20BrCl2N3O4S/c1-22(12-14-3-5-15(23)6-4-14)20(30)27(18-10-16(24)9-17(25)11-18)21-26-13-19(28(21)22)33(31,32)8-2-7-29/h3-6,9-11,13,29H,2,7-8,12H2,1H3/t22-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Dissociation constant for human Lymphocyte function associated antigen1 in LFA-1/ICAM-1 binding assay				J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB
					More data for this Ligand-Target Pair
Integrin alpha-L/beta-2 (Homo sapiens (Human))	BDBM50154476 ((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-(...) Show SMILES C[C@@]1(Cc2ccc(Br)cc2)C(=O)N(c2ncc(n12)S(=O)(=O)CCCO)c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C22H20BrCl2N3O4S/c1-22(12-14-3-5-15(23)6-4-14)20(30)27(18-10-16(24)9-17(25)11-18)21-26-13-19(28(21)22)33(31,32)8-2-7-29/h3-6,9-11,13,29H,2,7-8,12H2,1H3/t22-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay				J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB
					More data for this Ligand-Target Pair
Integrin alpha-L/beta-2 (Homo sapiens (Human))	BDBM50154476 ((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-(...) Show SMILES C[C@@]1(Cc2ccc(Br)cc2)C(=O)N(c2ncc(n12)S(=O)(=O)CCCO)c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C22H20BrCl2N3O4S/c1-22(12-14-3-5-15(23)6-4-14)20(30)27(18-10-16(24)9-17(25)11-18)21-26-13-19(28(21)22)33(31,32)8-2-7-29/h3-6,9-11,13,29H,2,7-8,12H2,1H3/t22-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Dissociation constant against human Lymphocyte function associated antigen1 in LFA-1/ICAM-1 binding assay				J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB
					More data for this Ligand-Target Pair