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BDBM50154482 5-(4-Bromo-benzyl)-7-(3,5-dichloro-phenyl)-5-methyl-6-oxo-6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-carbonitrile::CHEMBL188596

SMILES: CC1(Cc2ccc(Br)cc2)C(=O)N(c2ncc(C#N)n12)c1cc(Cl)cc(Cl)c1

InChI Key: InChIKey=MXCAAVRZKWSUKO-UHFFFAOYSA-N

Data: 1 Kd

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50154482   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Integrin beta-2/Leukocyte adhesion glycoprotein LFA-1 alpha


(Homo sapiens (Human))
BDBM50154482
PNG
(5-(4-Bromo-benzyl)-7-(3,5-dichloro-phenyl)-5-methy...)
Show SMILES CC1(Cc2ccc(Br)cc2)C(=O)N(c2ncc(C#N)n12)c1cc(Cl)cc(Cl)c1
Show InChI InChI=1S/C20H13BrCl2N4O/c1-20(9-12-2-4-13(21)5-3-12)18(28)26(16-7-14(22)6-15(23)8-16)19-25-11-17(10-24)27(19)20/h2-8,11H,9H2,1H3
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 190n/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay


J Med Chem 47: 5356-66 (2004)


Article DOI: 10.1021/jm049657b
BindingDB Entry DOI: 10.7270/Q2B857MB
More data for this
Ligand-Target Pair