BDBM50154487 3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-6-methanesulfonyl-3-methyl-1H-imidazo[1,2-a]imidazol-2-one::CHEMBL189819

SMILES: CC1(Cc2ccc(Br)cc2)C(=O)N(c2nc(cn12)S(C)(=O)=O)c1cc(Cl)cc(Cl)c1

InChI Key: InChIKey=QZDQYAWTHQIABF-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50154487   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-L/beta-2 (Homo sapiens (Human))	BDBM50154487 (3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-6-metha...) Show SMILES CC1(Cc2ccc(Br)cc2)C(=O)N(c2nc(cn12)S(C)(=O)=O)c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C20H16BrCl2N3O3S/c1-20(10-12-3-5-13(21)6-4-12)18(27)26(16-8-14(22)7-15(23)9-16)19-24-17(11-25(19)20)30(2,28)29/h3-9,11H,10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	920	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay				J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB
					More data for this Ligand-Target Pair