BDBM50154496 (R)-5-(4-Bromo-benzyl)-3-(3,5-dichloro-phenyl)-1,5-dimethyl-imidazolidine-2,4-dione::(R)-5-(4-bromobenzyl)-3-(3,5-dichlorophenyl)-1,5-dimethylimidazolidine-2,4-dione::CHEMBL367808
SMILES: CN1C(=O)N(C(=O)[C@@]1(C)Cc1ccc(Br)cc1)c1cc(Cl)cc(Cl)c1
InChI Key: InChIKey=FJNJHZQMQRVZEE-GOSISDBHSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154496 ((R)-5-(4-Bromo-benzyl)-3-(3,5-dichloro-phenyl)-1,5...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Cerep Curated by ChEMBL | Assay Description Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assay | Bioorg Med Chem Lett 15: 1161-4 (2005) Article DOI: 10.1016/j.bmcl.2004.12.007 BindingDB Entry DOI: 10.7270/Q2NP23W2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154496 ((R)-5-(4-Bromo-benzyl)-3-(3,5-dichloro-phenyl)-1,5...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair |