BDBM50154814 CHEMBL3775648

SMILES: Fc1ccc(cc1F)-n1nnc(C(=O)Nc2ccc(Oc3ccnc4[nH]ccc34)cc2)c1C(F)(F)F

InChI Key: InChIKey=IWYJNVYPJDNYTK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50154814   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50154814 (CHEMBL3775648) Show SMILES Fc1ccc(cc1F)-n1nnc(C(=O)Nc2ccc(Oc3ccnc4[nH]ccc34)cc2)c1C(F)(F)F Show InChI InChI=1S/C23H13F5N6O2/c24-16-6-3-13(11-17(16)25)34-20(23(26,27)28)19(32-33-34)22(35)31-12-1-4-14(5-2-12)36-18-8-10-30-21-15(18)7-9-29-21/h1-11H,(H,29,30)(H,31,35)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science and Technology Normal University Curated by ChEMBL					Assay Description Inhibition of cMet (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem Lett 26: 1680-4 (2016) BindingDB Entry DOI: 10.7270/Q2FF3V7R
					More data for this Ligand-Target Pair