BDBM50154816 CHEMBL3774862

SMILES: Fc1ccc(cc1)-n1nnc(C(=O)Nc2ccc(Oc3ccnc4[nH]ccc34)cc2)c1C(F)(F)F

InChI Key: InChIKey=PEYAQSGXFRHNQN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50154816   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50154816 (CHEMBL3774862) Show SMILES Fc1ccc(cc1)-n1nnc(C(=O)Nc2ccc(Oc3ccnc4[nH]ccc34)cc2)c1C(F)(F)F Show InChI InChI=1S/C23H14F4N6O2/c24-13-1-5-15(6-2-13)33-20(23(25,26)27)19(31-32-33)22(34)30-14-3-7-16(8-4-14)35-18-10-12-29-21-17(18)9-11-28-21/h1-12H,(H,28,29)(H,30,34)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science and Technology Normal University Curated by ChEMBL					Assay Description Inhibition of cMet (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem Lett 26: 1680-4 (2016) BindingDB Entry DOI: 10.7270/Q2FF3V7R
					More data for this Ligand-Target Pair