BDBM50154818 CHEMBL3775026

SMILES: FC(F)(F)c1c(nnn1-c1ccccc1)C(=O)Nc1ccc(Oc2ccnc3[nH]ccc23)cc1

InChI Key: InChIKey=VOMKUDNWGOHVBQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50154818   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50154818 (CHEMBL3775026) Show SMILES FC(F)(F)c1c(nnn1-c1ccccc1)C(=O)Nc1ccc(Oc2ccnc3[nH]ccc23)cc1 Show InChI InChI=1S/C23H15F3N6O2/c24-23(25,26)20-19(30-31-32(20)15-4-2-1-3-5-15)22(33)29-14-6-8-16(9-7-14)34-18-11-13-28-21-17(18)10-12-27-21/h1-13H,(H,27,28)(H,29,33)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science and Technology Normal University Curated by ChEMBL					Assay Description Inhibition of cMet (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem Lett 26: 1680-4 (2016) BindingDB Entry DOI: 10.7270/Q2FF3V7R
					More data for this Ligand-Target Pair