BDBM50154819 CHEMBL3775721

SMILES: Fc1cc(NC(=O)c2nnn(c2C(F)(F)F)-c2ccc(Cl)c(c2)C(F)(F)F)ccc1Oc1ccnc2[nH]ccc12

InChI Key: InChIKey=LKXFTIYQORPZAZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50154819   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50154819 (CHEMBL3775721) Show SMILES Fc1cc(NC(=O)c2nnn(c2C(F)(F)F)-c2ccc(Cl)c(c2)C(F)(F)F)ccc1Oc1ccnc2[nH]ccc12 Show InChI InChI=1S/C24H12ClF7N6O2/c25-15-3-2-12(10-14(15)23(27,28)29)38-20(24(30,31)32)19(36-37-38)22(39)35-11-1-4-18(16(26)9-11)40-17-6-8-34-21-13(17)5-7-33-21/h1-10H,(H,33,34)(H,35,39)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science and Technology Normal University Curated by ChEMBL					Assay Description Inhibition of cMet (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem Lett 26: 1680-4 (2016) BindingDB Entry DOI: 10.7270/Q2FF3V7R
					More data for this Ligand-Target Pair