BDBM50154828 CHEMBL3775275

SMILES: COc1ccc(cc1)-n1nnc(C(=O)Nc2ccc(Oc3ccnc4[nH]ccc34)cc2)c1C

InChI Key: InChIKey=JERXGCMGNSLRPZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50154828   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50154828 (CHEMBL3775275) Show SMILES COc1ccc(cc1)-n1nnc(C(=O)Nc2ccc(Oc3ccnc4[nH]ccc34)cc2)c1C Show InChI InChI=1S/C24H20N6O3/c1-15-22(28-29-30(15)17-5-9-18(32-2)10-6-17)24(31)27-16-3-7-19(8-4-16)33-21-12-14-26-23-20(21)11-13-25-23/h3-14H,1-2H3,(H,25,26)(H,27,31)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science and Technology Normal University Curated by ChEMBL					Assay Description Inhibition of cMet (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem Lett 26: 1680-4 (2016) BindingDB Entry DOI: 10.7270/Q2FF3V7R
					More data for this Ligand-Target Pair