BDBM50154833 CHEMBL3774854

SMILES: Cc1c(nnn1-c1ccc(F)c(Cl)c1)C(=O)Nc1ccc(Oc2ccnc3[nH]ccc23)c(F)c1

InChI Key: InChIKey=SNUDMZJVSZIJEX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50154833   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50154833 (CHEMBL3774854) Show SMILES Cc1c(nnn1-c1ccc(F)c(Cl)c1)C(=O)Nc1ccc(Oc2ccnc3[nH]ccc23)c(F)c1 Show InChI InChI=1S/C23H15ClF2N6O2/c1-12-21(30-31-32(12)14-3-4-17(25)16(24)11-14)23(33)29-13-2-5-20(18(26)10-13)34-19-7-9-28-22-15(19)6-8-27-22/h2-11H,1H3,(H,27,28)(H,29,33)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science and Technology Normal University Curated by ChEMBL					Assay Description Inhibition of cMet (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem Lett 26: 1680-4 (2016) BindingDB Entry DOI: 10.7270/Q2FF3V7R
					More data for this Ligand-Target Pair