BDBM50154909 CHEMBL3775082

SMILES: COc1ccc2NC(=O)\C(=C\c3cc(ccc3OC)C(=O)c3cc(OC)c(OC)c(OC)c3)c2c1

InChI Key: InChIKey=LIXLSIIYLVFCHM-RGVLZGJSSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50154909   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin beta chain (Sus scrofa)	BDBM50154909 (CHEMBL3775082) Show SMILES COc1ccc2NC(=O)\C(=C\c3cc(ccc3OC)C(=O)c3cc(OC)c(OC)c(OC)c3)c2c1 Show InChI InChI=1S/C27H25NO7/c1-31-18-7-8-21-19(14-18)20(27(30)28-21)11-16-10-15(6-9-22(16)32-2)25(29)17-12-23(33-3)26(35-5)24(13-17)34-4/h6-14H,1-5H3,(H,28,30)/b20-11+	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of porcine brain tubulin polymerization after 1 hr by fluorescence assay				Bioorg Med Chem 24: 1729-40 (2016) BindingDB Entry DOI: 10.7270/Q22809G0
					More data for this Ligand-Target Pair