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SMILES: Cc1ccncc1-c1cc(F)cc(c1)-n1nnc(n1)-c1ncc[nH]1

InChI Key: InChIKey=CZOBXSJMLFQPBT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50155006   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Rattus norvegicus (Rat))		BDBM50155006
PNG
(3-{3-Fluoro-5-[5-(1H-imidazol-2-yl)-tetrazol-2-yl]...)
Show SMILES Cc1ccncc1-c1cc(F)cc(c1)-n1nnc(n1)-c1ncc[nH]1
Show InChI InChI=1S/C16H12FN7/c1-10-2-3-18-9-14(10)11-6-12(17)8-13(7-11)24-22-16(21-23-24)15-19-4-5-20-15/h2-9H,1H3,(H,19,20)
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Article
PubMed
 3.5n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards Metabotropic glutamate receptor was determined by displacing [3H]-3-methoxy-5-(pyridin-2-ylethynyl)pyridine from rat cortica...

Bioorg Med Chem Lett 14: 5481-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.018
BindingDB Entry DOI: 10.7270/Q25M657V
More data for this
Ligand-Target Pair