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SMILES: [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](\c1c(-[#6])noc1-[#6])=[#6]-1\[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1

InChI Key: InChIKey=FLUSIOJERFHVHM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50155080   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mu-type opioid receptor


(MOUSE)		BDBM50155080
PNG
(4-[(3,5-Dimethyl-isoxazol-4-yl)-(8-furan-3-ylmethy...)
Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](\c1c(-[#6])noc1-[#6])=[#6]-1\[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1
Show InChI InChI=1S/C27H31N3O3/c1-4-28-27(31)21-7-5-20(6-8-21)26(25-17(2)29-33-18(25)3)22-13-23-9-10-24(14-22)30(23)15-19-11-12-32-16-19/h5-8,11-12,16,23-24H,4,9-10,13-15H2,1-3H3,(H,28,31)
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PC cid
PC sid
UniChem
Article
PubMed
 1.80n/an/an/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Binding affinity against mu opioid receptor in mouse hot plate test

Bioorg Med Chem Lett 14: 5493-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.004
BindingDB Entry DOI: 10.7270/Q2X34WZV
More data for this
Ligand-Target Pair